cancer spread prevention

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According to an Australian study, low-fat diets may slow the spread of cancer.

13 December, CANBERRA (Xinhua) — A low-fat diet might be the key to halting the spread of cancer, according to an Australian study.




Researchers from the South Australian Health and Medical Research Institute (SAHMRI) and the University of Adelaide dispelled the myth that diets have no effect on malignancies by discovering that cancers with IDH1 gene mutations cannot grow without lipids, which are contained in foods like butter.

The IDH1 mutation rewires a cell to alter enzymatic performance and is frequently observed in many blood, bone, and brain malignancies.

According to a press release from the SAHMRI, lead author Daniel Thomas, a clinical haematologist, "we replicated the results in a range of cancer types, comparing a regular diet with one that was completely fat-free and were surprised to find tumours with IDH1 were stopped in their tracks when starved of lipids."


Cancers with IDH1 mutations are hooked to lipids; they must consume them and produce them from scratch, unlike other tumours.

Thomas and his group will now try to confirm their findings over an extended period of time in humans.

He did, however, advise against consuming meals high in saturated fats if you have cancer that is IDH1 mutant.

The research group is hopeful that it will enable the SAHMRI to combine IDH1 targeting with proton and small molecule therapy, making it the first centre of its kind in the world.

Following the use of proton therapy or radiotherapy to treat IDH1 malignancies, Thomas remarked that these findings "may eventually lead to an increase in survivorship in patients who are in remission."

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