heart attack or stroke.

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 Combining high blood pressure with poor cholesterol may raise the chance of having a heart attack or stroke.




According to a recent study published in the journal Hypertension, lipoprotein(a) cholesterol may influence the association between hypertension and the risk of cardiovascular disease.

Highlights of the research

  • Increased levels of lipoprotein(a), a form of "bad" cholesterol, along with hypertension were found to increase a person's risk of developing cardiovascular disease and experiencing a major cardiovascular event like a heart attack or stroke over the course of a 14-year follow-up period in a study involving more than 6,000 men and women in the United States.
  • The researchers discovered that having elevated lipoprotein(a) levels, greater than or equal to 50mg/dL, along with hypertension enhanced a person's chance of developing cardiovascular disease or experiencing a severe cardiovascular event more than having hypertension alone.
 A major risk factor for cardiovascular disease is hypertension. A peak reading of 140 mmHg or more, a bottom reading of 90 mmHg or below, or the use of blood pressure medication were all considered to be indicators of hypertension in this study. The American Heart Association revised its definition of hypertension in 2017 to include readings of 80 mmHg or higher on the bottom or a top reading of 130 mmHg or higher.
 According to earlier research, having both hypertension and a lipid imbalance, or dyslipidemia, significantly raises a person's chance of developing cardiovascular disease. Less is known about the potential impact of lipoprotein(a) on cardiovascular disease risk in individuals with hypertension 

Cholesterol is transported through the blood via lipoproteins, which are composed of both protein and fat. Low-density lipoprotein (LDL), high-density lipoprotein (HDL), and lipoprotein(a), or Lp, are the three subtypes of lipoproteins (a). Similar to LDL cholesterol, lipoprotein(a) cholesterol can accumulate and deposit in the blood vessel walls, raising one's chance of having a heart attack or stroke.e study's authors.  
According to our research, hypertension appears to be the primary cause of cardiovascular risk in this heterogeneous group, said Rikhi. Additionally, when lipoprotein(a) levels were high, people with hypertension had an even increased risk of cardiovascular disease. More research is required because the interesting finding that lipoprotein(a) may alter the association between hypertension and cardiovascular disease reveals significant interactions or linkages between hypertension, lipoprotein(a), and cardiovascular disease.


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